Not losing weight on Mounjaro or Ozempic? Your genes could be the reason, says new study

What Happened

A study of nearly 28,000 people found that genetic variants influence how effectively weight loss drugs like Mounjaro and Ozempic work. Researchers identified a specific gene variant affecting GLP-1 receptor binding. People with two copies lost 1.5 kilograms more than those without variants over eight months. Indian doctors report similar varied responses among patients, suggesting genetic profiling could personalize obesity treatment.

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